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JAMB Biology 1984 Question 20

Question 20

Mendelian Inheritance

A man with a normal haemoglobin (AA) marries a woman who has sickle-cell haemoglobin (SS). They have a child who has a sickle-cell trait. Which of the following genotypes could be associated with the child's haemoglobin?

  1. A.AA
  2. B.OO
  3. C.AO
  4. D.AS
  5. E.SS.
Show the answer and explanation

Answer: D (AS)

Explanation

The child gets A from the father and S from the mother, so every child is AS, which is the sickle-cell trait (carrier).